The lupus anticoagulant: results from 2257 patients attending a high-risk pregnancy clinic

Author:

Clark Christine A.12,Davidovits Judith234,Spitzer Karen A.12,Laskin Carl A.24

Affiliation:

1. Mt. Sinai Hospital, Toronto, Ontario, Canada;

2. LifeQuest Centre for Reproductive Medicine, Toronto, Ontario, Canada;

3. Division of Clinical Pharmacology, Hospital for Sick Children, Toronto, Ontario, Canada; and

4. Departments of Medicine, Obstetrics and Gynecology, and Clinical Pharmacology, University of Toronto, Toronto, Ontario, Canada

Abstract

Key Points Only 62 (2.7%) of 2257 high-risk patients tested positive for LAC over 6 years; only 5 (0.02%) with early recurrent miscarriage tested positive. The 2 assays recommended by ISTH guidelines were less effective than our 4-assay panel at capturing and describing LAC-positive patients.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference39 articles.

1. Lupus anticoagulant and pregnancy.;Lubbe;Am J Obstet Gynecol,1985

2. Obstetric complications associated with the lupus anticoagulant.;Branch;N Engl J Med,1985

3. Thrombosis in systemic lupus erythematosus despite circulating anticoagulants.;Bowie;J Lab Clin Med,1963

4. Thrombosis in patients with the lupus anticoagulant.;Mueh;Ann Intern Med,1980

5. Pathophysiology of the antiphospholipid syndrome (APS).;Meroni;Rev Med Interne,2012

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3