CD40L expression permits CD8+ T cells to execute immunologic helper functions-Reference-Cited by-同舟云学术

CD40L expression permits CD8+ T cells to execute immunologic helper functions

Published:2013-07-18 Issue:3 Volume:122 Page:405-412
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Frentsch Marco¹,Stark Regina¹,Matzmohr Nadine¹,Meier Sarah¹,Durlanik Sibel¹,Schulz Axel R.¹,Stervbo Ulrik¹,Jürchott Karsten²,Gebhardt Friedemann³,Heine Guido⁴,Reuter Morgan A.⁵,Betts Michael R.⁵,Busch Dirk³,Thiel Andreas¹

Affiliation:

1. Regenerative Immunology and Aging, Berlin-Brandenburg Center for Regenerative Therapies, Charité University Medicine, Berlin, Germany;

2. Institute for Theoretical Biology, Humboldt University of Berlin, Berlin, Germany;

3. Institute for Medical Microbiology, Technical University Munich, Munich, Germany;

4. Allergie-Centrum-Charité, Charité University Medicine, Berlin, Germany; and

5. Department of Microbiology, University of Pennsylvania, Philadelphia, PA

Abstract

Key Points A major part of CD8+ memory T cells expresses CD40L, the key molecule for T-cell–dependent help. CD40L-expressing CD8+ T cells resemble functional CD4+ helper T cells.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/3/405/1371877/405.pdf

Reference40 articles.

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3. Cross-priming in health and disease.;Kurts;Nat Rev Immunol,2010

4. Autophagy in MHC class II antigen processing.;Strawbridge;Curr Opin Immunol,2007

5. CD40 and CD154 in cell-mediated immunity.;Grewal;Annu Rev Immunol,1998

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