Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance-Reference-Cited by-同舟云学术

Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance

Published:2014-03-13 Issue:11 Volume:123 Page:1720-1728
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Buscarlet Manuel¹²,Krasteva Veneta¹²,Ho Lena³,Simon Camille¹²,Hébert Josée⁴,Wilhelm Brian¹,Crabtree Gerald R.³,Sauvageau Guy¹,Thibault Pierre¹⁵,Lessard Julie A.¹²

Affiliation:

1. Institute for Research in Immunology and Cancer, Montreal, QC, Canada;

2. Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada;

3. Department of Pathology and Department of Developmental Biology, Howard Hughes Medical Institute, Stanford University, CA;

4. Leukemia Cell Bank of Quebec and Division of Hematology, Maisonneuve-Rosemont Hospital, Montreal, QC, Canada; and

5. Department of Chemistry, Faculty of Arts and Science, Université de Montréal, Montreal, QC, Canada

Abstract

Key Points Quantitative proteomics identifies BRG as the main ATPase of BAF complexes expressed in leukemia. BRG is essential for the proliferation of leukemic cells.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/11/1720/537248/1720.pdf

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