Mice with a deficiency in CLEC-2 are protected against deep vein thrombosis-Reference-Cited by-同舟云学术

Mice with a deficiency in CLEC-2 are protected against deep vein thrombosis

Published:2017-04-06 Issue:14 Volume:129 Page:2013-2020
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Payne Holly¹,Ponomaryov Tatyana¹,Watson Steve P.¹^ORCID,Brill Alexander¹^ORCID

Affiliation:

1. Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom

Abstract

Key Points Absence of CLEC-2 abrogates venous thrombosis. Podoplanin expression is upregulated in the vessel wall and correlates with the degree of thrombosis.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/14/2013/1400016/blood742999.pdf

Reference46 articles.

1. Podoplanin: emerging functions in development, the immune system, and cancer;Astarita;Front Immunol,2012

2. Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors;Schacht;Am J Pathol,2005

3. CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis;May;Blood,2009

4. Essential in vivo roles of the C-type lectin receptor CLEC-2: embryonic/neonatal lethality of CLEC-2-deficient mice by blood/lymphatic misconnections and impaired thrombus formation of CLEC-2-deficient platelets;Suzuki-Inoue;J Biol Chem,2010

5. CLEC-2 is not required for platelet aggregation at arteriolar shear;Hughes;J Thromb Haemost,2010

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