Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML-Reference-Cited by-同舟云学术

Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML

Published:2014-04-10 Issue:15 Volume:123 Page:2412-2415
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Havelange Violaine¹²³⁴,Ranganathan Parvathi¹²,Geyer Susan¹²⁵,Nicolet Deedra¹²⁵,Huang Xiaomeng¹²,Yu Xueyan¹²,Volinia Stefano²³,Kornblau Steven M.⁶,Andreeff Michael⁶,Croce Carlo M.²³,Marcucci Guido¹²³,Bloomfield Clara D.¹²,Garzon Ramiro¹²

Affiliation:

1. Division of Hematology,

2. The Comprehensive Cancer Center, and

3. Department of Molecular Virology, Immunology and Cancer Genetics, The Ohio State University, Columbus, OH;

4. Hematological Department, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium;

5. Alliance for Clinical Trials in Oncology Statistics and Data Center; and

6. Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX

Abstract

Key Points High miR-10 family expression levels in AML patients are associated with achieving complete remission to induction chemotherapy. Functional experiments did not show any impact of miR-10a-5p in AML blast growth or survival at baseline conditions or after chemotherapy.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/15/2412/1375122/2412.pdf

Reference15 articles.

1. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype.;Falini;N Engl J Med,2005

2. Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives.;Falini;Curr Opin Oncol,2009

3. Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?;Mrózek;Blood,2007

4. Targeting microRNAs in cancer: rationale, strategies and challenges.;Garzon;Nat Rev Drug Discov,2010

5. The prognostic and functional role of microRNAs in acute myeloid leukemia.;Marcucci;Blood,2011

Cited by 43 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Title: "Exploring miR-10a/b Expression in Leukemia Cell Lines: Implications for Biomarker Discovery in Acute Leukemias" (Preprint);2024-07-13

2. Assessment of miRNA-10b Expression Levels as a Potential Precursor to Metastasis in Localized and Locally Advanced/Metastatic Breast Cancer among Iraqi Patients;International Journal of Breast Cancer;2024-02-28

3. Exosomes from bone marrow mesenchymal stem cells decrease chemosensitivity of acute myeloid leukemia cells via delivering miR-10a;Biochemical and Biophysical Research Communications;2022-09

4. Nucleophosmin 1: from its pathogenic role to a tantalizing therapeutic target in acute myeloid leukemia;Hematology;2022-05-27

5. Implication of microRNAs in Carcinogenesis with Emphasis on Hematological Malignancies and Clinical Translation;International Journal of Molecular Sciences;2022-05-23