A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia-Reference-Cited by-同舟云学术

A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia

Published:2014-03-27 Issue:13 Volume:123 Page:2026-2033
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Tong Wing H.¹,Pieters Rob¹²,Kaspers Gertjan J. L.³,te Loo D. Maroeska W. M.⁴,Bierings Marc B.⁵,van den Bos Cor⁶,Kollen Wouter J. W.⁷,Hop Wim C. J.⁸,Lanvers-Kaminsky Claudia⁹,Relling Mary V.¹⁰,Tissing Wim J. E.¹¹,van der Sluis Inge M.¹

Affiliation:

1. Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children’s Hospital, Rotterdam, The Netherlands;

2. Dutch Childhood Oncology Group, The Hague, The Netherlands;

3. Department of Pediatric Oncology-Hematology, VU University Medical Center, Amsterdam, The Netherlands;

4. Department of Pediatric Hematology and Oncology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands;

5. Department of Pediatric Hematology-Oncology, University Medical Center Utrecht-Wilhelmina Children’s Hospital, Utrecht, The Netherlands;

6. Department of Pediatric Oncology, Academic Medical Center-Emma Children’s Hospital, Amsterdam, The Netherlands;

7. Department of Pediatric Immunology, Hemato-Oncology and Stem Cell Transplantation, Leiden University Medical Center, Leiden, The Netherlands;

8. Department of Biostatistics, Erasmus MC-University Medical Center, Rotterdam, The Netherlands;

9. Department of Pediatric Hematology/Oncology, University Children’s Hospital, Muenster, Germany;

10. Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, TN; and

11. Department of Pediatric Oncology and Hematology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands

Abstract

Key Points Use of native E coli asparaginase in induction leads to high hypersensitivity rates to PEGasparaginase in intensification. Switching to Erwinia asparaginase leads to effective asparaginase activity levels in most patients who experienced an allergy to PEGasparaginase.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/13/2026/1374791/2026.pdf

Reference35 articles.

1. Treatment of acute lymphoblastic leukemia.;Pui;N Engl J Med,2006

2. Characterization of apoptotic phenomena induced by treatment with L-asparaginase in NIH3T3 cells.;Bussolati;Exp Cell Res,1995

3. Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL.;Stams;Blood,2003

4. Intensive high-dose asparaginase consolidation improves survival for pediatric patients with T cell acute lymphoblastic leukemia and advanced stage lymphoblastic lymphoma: a Pediatric Oncology Group study.;Amylon;Leukemia,1999

5. Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01.;Silverman;Blood,2001

Cited by 184 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Asparaginase: Optimizing Efficacy and Minimizing Toxicity in Pediatric and AYA ALL/LBL;Clinical Lymphoma Myeloma and Leukemia;2024-09

2. l‐Asparaginase Bio‐Betters: Insight Into Current Formulations, Optimization Strategies and Future Bioengineering Frontiers in Anti‐Cancer Drug Development;Advanced Therapeutics;2024-08-19

3. A Refined Population Pharmacokinetic Model–Based Guideline for Individualized PEGasparaginase Dosing in Pediatric Acute Lymphoblastic Leukemia;Therapeutic Drug Monitoring;2024-08-13

4. The correlation of asparaginase enzyme activity levels after PEG‐asparaginase administration with clinical characteristics and adverse effects in Chinese paediatric patients with acute lymphoblastic leukaemia;British Journal of Haematology;2024-06-27

5. In Silico-Driven Engineering ofHalomonas elongataL-Asparaginase: Towards Enhanced Proteolytic Resistance in Lymphoblastic Leukemia;2024-06-08