Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro-Reference-Cited by-同舟云学术

Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro

Published:2014-01-30 Issue:5 Volume:123 Page:687-696
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Danesh Ali¹²,Inglis Heather C.¹,Jackman Rachael P.¹,Wu Shiquan¹,Deng Xutao¹,Muench Marcus O.¹²,Heitman John W.¹,Norris Philip J.¹²³

Affiliation:

1. Blood Systems Research Institute, San Francisco, CA;

2. Department of Laboratory Medicine, and

3. Department of Medicine, University of California, San Francisco, San Francisco, CA

Abstract

Key Points Exosomes in blood are proinflammatory and may contribute to transfusion-related immune modulation. Exosomes act via antigen-presenting cells to potentiate T-cell survival and mitogen-induced proliferation.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/5/687/1378938/687.pdf

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