Risk of multiple primary malignancies following treatment of Hodgkin lymphoma

Author:

van Eggermond Anna M.1,Schaapveld Michael12,Lugtenburg Pieternella J.3,Krol Augustinus D. G.4,de Boer Jan Paul5,Zijlstra Josée M.6,Raemaekers John M. M.7,Kremer Leontien C. M.8,Roesink Judith M.9,Louwman Marieke W. J.10,Aleman Berthe M. P.11,van Leeuwen Flora E.1

Affiliation:

1. Department of Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands;

2. Comprehensive Cancer Center, Utrecht, The Netherlands;

3. Department of Hematology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands;

4. Division of Radiotherapy, Leiden University Medical Center, Leiden, The Netherlands;

5. Department of Hematology, The Netherlands Cancer Institute, Amsterdam, The Netherlands;

6. Department of Hematology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands;

7. Department of Hematology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands;

8. Department of Pediatric Oncology, Emma Children’s Hospital/Academic Medical Center, Amsterdam, The Netherlands;

9. Department of Radiotherapy, University Medical Center Utrecht, Utrecht, The Netherlands;

10. Comprehensive Cancer Center South, Eindhoven, The Netherlands; and

11. Department of Radiotherapy, The Netherlands Cancer Institute, Amsterdam, The Netherlands

Abstract

Key Points Hodgkin lymphoma survivors who developed a second malignancy remain at high risk of developing subsequent malignancies. Treatment options for these malignancies may be more restricted making early detection especially important to improving outcome.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Reference45 articles.

1. Integraal Kankercentrum Nederland Comprehensive Cancer Centre The Netherlands. Dutch cancer figures. http://cijfersoverkanker.nl/selecties/Dataset_2/img511e01347d788. Accessed June 29, 2012

2. State of the art in the treatment of Hodgkin lymphoma.;Borchmann;Nat Rev Clin Oncol,2012

3. Second malignant neoplasms among long-term survivors of Hodgkin’s disease: a population-based evaluation over 25 years.;Dores;J Clin Oncol,2002

4. Long-term solid cancer risk among 5-year survivors of Hodgkin’s lymphoma.;Hodgson;J Clin Oncol,2007

5. Second malignancy after Hodgkin disease treated with radiation therapy with or without chemotherapy: long-term risks and risk factors.;Ng;Blood,2002

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