Platelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice-Reference-Cited by-同舟云学术

Platelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice

Published:2015-10-08 Issue:15 Volume:126 Page:1835-1843
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Miyakawa Kazuhisa¹²,Joshi Nikita²³,Sullivan Bradley P.¹,Albee Ryan³,Brandenberger Christina¹,Jaeschke Hartmut⁴,McGill Mitchell R.⁴,Scott Michael A.¹,Ganey Patricia E.²³,Luyendyk James P.¹²,Roth Robert A.²³

Affiliation:

1. Department of Pathobiology and Diagnostic Investigation,

2. Institute for Integrative Toxicology,

3. Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI; and

4. Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS

Abstract

Key Points Platelets and PAR-4 contribute to the progression of APAP-induced liver injury in mice through independent pathways.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/15/1835/1390057/1835.pdf

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