Haploidentical hematopoietic transplantation from KIR ligand–mismatched donors with activating KIRs reduces nonrelapse mortality-Reference-Cited by-同舟云学术

Haploidentical hematopoietic transplantation from KIR ligand–mismatched donors with activating KIRs reduces nonrelapse mortality

Published:2015-05-14 Issue:20 Volume:125 Page:3173-3182
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Mancusi Antonella¹,Ruggeri Loredana¹,Urbani Elena¹,Pierini Antonio¹,Massei Maria Speranza¹,Carotti Alessandra¹,Terenzi Adelmo¹,Falzetti Franca¹,Tosti Antonella¹,Topini Fabiana¹,Bozza Silvia²,Romani Luigina²,Tognellini Rita³,Stern Martin⁴,Aversa Franco⁵,Martelli Massimo F.¹,Velardi Andrea¹

Affiliation:

1. Division of Hematology and Clinical Immunology and Bone Marrow Transplant Program, Department of Medicine and

2. Division of Microbiology, Department of Experimental Medicine, University of Perugia, Perugia, Italy;

3. Blood Bank, Ospedale Santa Maria della Misericordia, Perugia, Italy;

4. Immunotherapy Laboratory, Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland; and

5. Division of Hematology and Bone Marrow Transplant Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy

Abstract

Key Points Haploidentical transplantation from KIR ligand–mismatched donors with activating KIRs reduces nonrelapse mortality and improves survival. Activating KIR genetics should be considered when selecting donors for T cell–depleted haploidentical hematopoietic transplantation.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/20/3173/1386133/3173.pdf

Reference72 articles.

1. Haplo-BMT: which approach? [commentary];Velardi;Blood,2013

2. Haploidentical hematopoietic transplantation: current status and future perspectives.;Reisner;Blood,2011

3. Successful engraftment of T-cell-depleted haploidentical “three-loci” incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum.;Aversa;Blood,1994

4. Treatment of high-risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype.;Aversa;N Engl J Med,1998

5. Full haplotype-mismatched hematopoietic stem-cell transplantation: a phase II study in patients with acute leukemia at high risk of relapse.;Aversa;J Clin Oncol,2005

Cited by 99 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Histocompatibility assessment in hematopoietic stem cell transplantation: recommendations from the Italian Society for Immunogenetics and Transplantation Biology (Associazione Italiana di Immunogenetica e Biologia dei Trapianti - AIBT);BLOOD TRANSFUS-ITALY;2024

2. Impact of Natural Killer Cell-Associated Factors on Acute Leukemia Outcomes after Haploidentical Hematopoietic Stem Cell Transplantation with αβ T Cell Depletion in a Pediatric Cohort;Transplantation and Cellular Therapy;2024-04

3. Impact of KIR-HLA Genotype on Natural-Killer-Cell-Based Immunotherapy for Preventing Hepatocellular Carcinoma after Living-Donor Liver Transplantation;Cancers;2024-01-26

4. Investigation of KIR/HLA relationship and other clinical variables after T-cell-replete haploidentical bone marrow transplantation in patients with acute myeloid leukemia (AML);BMC Immunology;2023-06-20

5. Probability of allogeneic hematopoietic stem cell transplant failure depending on the recipient's killer immunoglobulin-like receptor genotype;Transplantologiya. The Russian Journal of Transplantation;2023-03-17