Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation-Reference-Cited by-同舟云学术

Critical role of sphingosine-1-phosphate receptor 2 (S1PR2) in acute vascular inflammation

Published:2013-07-18 Issue:3 Volume:122 Page:443-455
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Zhang Guoqi¹,Yang Li¹,Kim Gab Seok¹,Ryan Kieran¹,Lu Shulin²,O’Donnell Rebekah K.³,Spokes Katherine⁴,Shapiro Nathan²,Aird William C.⁴,Kluk Michael J.⁵,Yano Kiichiro²,Sanchez Teresa¹

Affiliation:

1. Departments of Surgery and Emergency Medicine,

2. Department of Emergency Medicine,

3. Department of Pathology, and

4. Department of Medicine, The Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, and

5. Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA

Abstract

Key Points Endothelial S1PR2 plays a critical role in the induction of vascular permeability and vascular inflammation during endotoxemia. S1PR2 could be a novel therapeutic target to promote vascular integrity in inflammatory vascular disorders.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/3/443/1372371/443.pdf

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3. Vascular endothelium as a contributor of plasma sphingosine 1-phosphate.;Venkataraman;Circ Res,2008

4. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1.;Lee;Science,1998

5. Structural and functional characteristics of S1P receptors.;Sanchez;J Cell Biochem,2004

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