Subcellular mislocalization of the transcription factor NF-E2 in erythroid cells discriminates prefibrotic primary myelofibrosis from essential thrombocythemia-Reference-Cited by-同舟云学术

Subcellular mislocalization of the transcription factor NF-E2 in erythroid cells discriminates prefibrotic primary myelofibrosis from essential thrombocythemia

Published:2013-07-04 Issue:1 Volume:122 Page:93-99
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Aumann Konrad¹,Frey Anna-Verena¹,May Annette M.¹,Hauschke Dieter²,Kreutz Clemens³,Marx Jan P.⁴,Timmer Jens³,Werner Martin¹,Pahl Heike L.⁴

Affiliation:

1. Institute of Pathology, and

2. Department of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Freiburg, Germany;

3. Department of Physics and Freiburg Centre for Biosystems Analysis (ZBSA), University of Freiburg, Freiburg, Germany; and

4. Division of Molecular Hematology, University Medical Center Freiburg, Freiburg, Germany

Abstract

Key Points The transcription factor NF-E2 is mislocalized in patients with primary myelofibrosis. Immunohistochemical staining for NF-E2 distinguishes essential thrombocythemia from primary myelofibrosis.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/1/93/1369193/93.pdf

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