Redirecting T-cell specificity by introducing a tumor-specific chimeric antigen receptor
Author:
Affiliation:
1. Division of Pediatrics, University of Texas M. D. Anderson Cancer Center, Houston; and
2. Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/116/7/1035/1333755/zh803310001035.pdf
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3. Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors.;Eshhar;Proc Natl Acad Sci U S A,1993
4. Specific recognition and killing of glioblastoma multiforme by interleukin 13-zetakine redirected cytolytic T cells.;Kahlon;Cancer Res,2004
5. Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia.;Imai;Leukemia,2004
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