Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice

Author:

Kwon Hye-Sook1,Logan Aaron C.2,Chhabra Akanksha1,Pang Wendy W.1,Czechowicz Agnieszka345,Tate Keri6,Le Alan1,Poyser Jessica1,Hollis Roger7,Kelly Benjamin V.8,Kohn Donald B.79,Weissman Irving L.4101112,Prohaska Susan S.1,Shizuru Judith A.131012

Affiliation:

1. Division of Blood and Marrow Transplantation, Department of Medicine, School of Medicine, Stanford University, Stanford, CA;

2. Division of Malignant Hematology and Blood and Marrow Transplantation, Department of Medicine, University of California, San Francisco, San Francisco, CA;

3. Division of Stem Cell Transplantation and Regenerative Medicine, Department of Pediatrics,

4. Department of Pathology, and

5. Department of Developmental Biology, School of Medicine, Stanford University, Stanford, CA;

6. Stanford Laboratory for Cell and Gene Medicine, Stanford University, Palo Alto, CA;

7. Department of Microbiology, Immunology, and Molecular Genetics,

8. Department of Orthopaedic Surgery, David Geffen School of Medicine, and

9. Division of Hematology/Oncology, Department of Pediatrics, University of California, Los Angeles, Los Angeles, CA; and

10. Stanford Cancer Institute,

11. Ludwig Center for Cancer Stem Cell Research and Medicine, and

12. Institute for Stem Cell Biology and Regenerative Medicine, School of Medicine, Stanford University, Stanford, CA

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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