Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma-Reference-Cited by-同舟云学术

Populational equilibrium through exosome-mediated Wnt signaling in tumor progression of diffuse large B-cell lymphoma

Published:2014-04-03 Issue:14 Volume:123 Page:2189-2198
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Koch Raphael¹,Demant Martin¹,Aung Thiha¹,Diering Nina¹,Cicholas Anna¹,Chapuy Bjoern²,Wenzel Dirk³,Lahmann Marlen¹,Güntsch Annemarie¹,Kiecke Christina¹,Becker Sabrina¹,Hupfeld Timo¹,Venkataramani Vivek¹,Ziepert Marita⁴,Opitz Lennart⁵,Klapper Wolfram⁶,Trümper Lorenz¹,Wulf Gerald G.¹

Affiliation:

1. Department of Hematology and Oncology, Georg-August-University, Goettingen, Germany;

2. Dana-Farber Cancer Institute, Boston, MA;

3. Max-Planck Institute for Biophysical Chemistry, Goettingen, Germany;

4. Institute for Medical Informatics, Statistics and Epidemiology, Leipzig, Germany;

5. Functional Genomics Center Zurich, Zurich, Switzerland; and

6. Pathology, Hematopathology Section and Lymph Node Registry, Kiel, Germany

Abstract

Key Points Diffuse large B-cell lymphomas are composed of clonogenic side population (SP) cells and non-SP cells organized in a dynamic equilibrium. Exosome-mediated Wnt signaling modulates transitions of cell states and tumor progression amenable to drug targeting.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/123/14/2189/1375147/2189.pdf

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