CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia-Reference-Cited by-同舟云学术

CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia

Published:2015-03-26 Issue:13 Volume:125 Page:2087-2094
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Arieta Kuksin Christina¹,Gonzalez-Perez Gabriela¹,Minter Lisa M.¹²

Affiliation:

1. Department of Veterinary and Animal Sciences, and

2. Program in Molecular and Cellular Biology, University of Massachusetts Amherst, Amherst, MA

Abstract

Key PointsNF-κB differentially regulates CXCR4 expression on naïve and pathogenic CD8+ T cells. CXCR4 expression on pathogenic T cells facilitates their trafficking to the BM in a mouse model of AA.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/13/2087/1383910/2087.pdf

Reference71 articles.

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4. Aplastic anemia: what have we learned from animal models and from the clinic.;Scheinberg;Semin Hematol,2013

5. Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia.;Roderick;J Exp Med,2013

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