MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development-Reference-Cited by-同舟云学术

MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development

Published:2015-03-19 Issue:12 Volume:125 Page:1910-1921
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Sheikh Bilal N.¹²,Lee Stanley C. W.¹²,El-Saafin Farrah¹²,Vanyai Hannah K.¹²,Hu Yifang¹,Pang Swee Heng Milon¹²,Grabow Stephanie¹²,Strasser Andreas¹²,Nutt Stephen L.¹²,Alexander Warren S.¹²,Smyth Gordon K.¹³,Voss Anne K.¹²,Thomas Tim¹²

Affiliation:

1. The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia; and

2. Department of Medical Biology, and

3. Department of Mathematics and Statistics, University of Melbourne, Melbourne, Victoria, Australia

Abstract

Key Points Regulation of genes required for B-cell progenitor proliferation is exquisitely dependent on Moz gene dosage. Loss of one Moz allele delays the onset of MYC-driven lymphoma by 3.9-fold.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/12/1910/1383638/1910.pdf

Reference59 articles.

1. The complex language of chromatin regulation during transcription.;Berger;Nature,2007

2. Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation.;Cui;Cell Stem Cell,2009

3. The role of chromatin modifiers in normal and malignant hematopoiesis.;Butler;Blood,2013

4. Epigenetic regulation of normal and malignant hematopoiesis.;Rice;Oncogene,2007

5. ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.;Doyon;Mol Cell,2006

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