The ABCC4 membrane transporter modulates platelet aggregation-Reference-Cited by-同舟云学术

The ABCC4 membrane transporter modulates platelet aggregation

Published:2015-11-12 Issue:20 Volume:126 Page:2307-2319
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Cheepala Satish B.¹,Pitre Aaron¹^ORCID,Fukuda Yu¹,Takenaka Kazumasa¹,Zhang Yuanyuan¹,Wang Yao¹,Frase Sharon²,Pestina Tamara³,Gartner T. Kent⁴,Jackson Carl⁵,Schuetz John D.¹

Affiliation:

1. Department of Pharmaceutical Sciences,

2. Cellular Imaging Shared Resource, and

3. Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN;

4. Department of Biology, University of Memphis, Memphis, TN; and

5. Academic Programs, St. Jude Children's Research Hospital, Memphis, TN

Abstract

Key Points The ABC transporter, ABCC4, localizes to the platelet plasma membrane and regulates aggregation by exporting cAMP and antithrombotic drugs.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/20/2307/1389764/2307.pdf

Reference40 articles.

1. The multidrug resistance-associated protein 4 (MRP4) appears as a functional carrier of prostaglandins regulated by oxytocin in the bovine endometrium.;Lacroix-Pépin;Endocrinology,2011

2. Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling.;Conti;Annu Rev Biochem,2007

3. Cyclic nucleotides and phosphodiesterases in platelets.;Haslam;Thromb Haemost,1999

4. The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage.;Jedlitschky;Blood,2004

5. Role of MRP4 (ABCC4) in platelet adenine nucleotide-storage: evidence from patients with delta-storage pool deficiencies.;Jedlitschky;Am J Pathol,2010

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