Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome-Reference-Cited by-同舟云学术

Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome

Published:2015-03-05 Issue:10 Volume:125 Page:1633-1642
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Sharda Anish¹,Kim Sarah H.¹,Jasuja Reema¹,Gopal Srila¹,Flaumenhaft Robert¹,Furie Barbara C.¹,Furie Bruce¹

Affiliation:

1. Division of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA; and Department of Medicine, Harvard Medical School, Boston, MA

Abstract

Key Points Hermansky-Pudlak syndrome exhibits impaired granule exocytosis and PDI secretion that contribute to its associated bleeding disorder. Endothelial cells deficient in HPS6 show defective secretion of granules, including Weibel-Palade bodies.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/10/1633/1383402/1633.pdf

Reference30 articles.

1. Albinism and abnormal platelet function.;Logan;N Engl J Med,1971

2. The platelet defect associated with albumism.;Hardisty;Br J Haematol,1972

3. Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6.;Zhang;Nat Genet,2003

4. The Hermansky-Pudlak syndrome 3 (cocoa) protein is a component of the biogenesis of lysosome-related organelles complex-2 (BLOC-2).;Gautam;J Biol Chem,2004

5. Characterization of BLOC-2, a complex containing the Hermansky-Pudlak syndrome proteins HPS3, HPS5 and HPS6.;Di Pietro;Traffic,2004

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