PARP1 is required for chromosomal translocations-Reference-Cited by-同舟云学术

PARP1 is required for chromosomal translocations

Published:2013-05-23 Issue:21 Volume:121 Page:4359-4365
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Wray Justin¹,Williamson Elizabeth A.¹,Singh Sudha B.¹,Wu Yuehan¹,Cogle Christopher R.¹,Weinstock David M.²,Zhang Yu³,Lee Suk-Hee⁴,Zhou Daohong⁵,Shao Lijian⁵,Hauer-Jensen Martin⁵,Pathak Rupak⁵,Klimek Virginia⁶,Nickoloff Jac A.⁷,Hromas Robert¹

Affiliation:

1. Department of Medicine, University of Florida College of Medicine, Gainesville, FL;

2. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;

3. Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY;

4. Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN;

5. Department of Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock, AR;

6. Department of Hematology, Memorial Sloan-Kettering Cancer Center, New York, NY; and

7. Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO

Abstract

Key Points Chromosomal translocations are mediated by PARP1 and can be suppressed by the clinical PARP1 inhibitors.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/21/4359/1366206/4359.pdf

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4. Induction and repair of DNA double strand breaks: the increasing spectrum of non-homologous end joining pathways.;Mladenov;Mutat Res,2011

5. Chromatin structural elements and chromosomal translocations in leukemia.;Zhang;DNA Repair (Amst),2006

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