Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network-Reference-Cited by-同舟云学术

Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network

Published:2013-03-07 Issue:10 Volume:121 Page:1875-1885
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Stalker Timothy J.¹,Traxler Elizabeth A.¹,Wu Jie¹,Wannemacher Kenneth M.¹,Cermignano Samantha L.¹,Voronov Roman²,Diamond Scott L.²,Brass Lawrence F.¹

Affiliation:

1. Departments of Medicine and Pharmacology and the

2. Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, PA

Abstract

Key Points Hemostatic plugs develop a regional architecture defined by the extent of platelet activation and packing density. The regional composition of a hemostatic plug is due to the interaction of local conditions with the platelet-signaling network.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/10/1875/1363983/1875.pdf

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