Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia-Reference-Cited by-同舟云学术

Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia

Published:2013-03-07 Issue:10 Volume:121 Page:1783-1794
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Flick Matthew J.¹,Du XinLi¹,Prasad Joni M.¹,Raghu Harini¹,Palumbo Joseph S.¹,Smeds Emanuel²,Höök Magnus²,Degen Jay L.¹

Affiliation:

1. Division of Experimental Hematology and Cancer and Blood Diseases Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH; and

2. Center for Infectious and Inflammatory Diseases, Institute for Biosciences and Technology, Texas A&M Health Science Center, Houston, TX

Abstract

Key PointsEliminating the binding motif on fibrinogen for ClfA, but not leukocyte integrin Mac-1, improves host survival in Staphylococcus aureus septicemia.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/10/1783/1363698/1783.pdf

Reference50 articles.

1. Staphylococcus aureus infections.;Lowy;N Engl J Med,1998

2. Adherence of staphylococci to intravascular catheters.;Kristinsson;J Med Microbiol,1989

3. Community-acquired methicillin-resistant Staphylococcus aureus infections.;Maltezou;Int J Antimicrob Agents,2006

4. Contribution of coagulases towards Staphylococcus aureus disease and protective immunity.;Cheng;PLoS Pathog,2010

5. Surface protein adhesins of Staphylococcus aureus.;Foster;Trends Microbiol,1998

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