α1-Antitrypsin infusion for treatment of steroid-resistant acute graft-versus-host disease-Reference-Cited by-同舟云学术

α1-Antitrypsin infusion for treatment of steroid-resistant acute graft-versus-host disease

Published:2018-03-22 Issue:12 Volume:131 Page:1372-1379
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Magenau John M.¹,Goldstein Steven C.¹,Peltier Dan¹,Soiffer Robert J.²,Braun Thomas³,Pawarode Attaphol¹,Riwes Mary M.¹,Kennel Maggi¹,Antin Joseph H.²,Cutler Corey S.²,Ho Vincent T.²,Alyea Edwin P.²,Parkin Brian L.¹,Yanik Gregory A.¹,Choi Sung Won¹,Lewis Eli C.⁴,Dinarello Charles A.⁵,Koreth John²,Reddy Pavan¹^ORCID

Affiliation:

1. Blood and Marrow Transplantation Program, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI;

2. Stem Cell/Bone Marrow Transplantation Program, Division of Hematologic Malignancy, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA;

3. Department of Biostatistics, University of Michigan, Ann Arbor, MI;

4. Department of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev, Beer-Sheva, Israel; and

5. Department Medicine and Immunology, University of Colorado, Aurora, CO

Abstract

Key PointsAAT infusion produced a high proportion of durable clinical responses in SR-aGVHD. AAT is associated with minimal toxicity and low rates of infection in patients with SR-aGVHD at significant risk for mortality.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/131/12/1372/1405639/blood815746.pdf

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4. Early antithymocyte globulin therapy improves survival in patients with steroid-resistant acute graft-versus-host disease;MacMillan;Biol Blood Marrow Transplant,2002

5. Treatment of steroid-resistant acute graft-versus-host disease with anti-thymocyte globulin;Khoury;Bone Marrow Transplant,2001

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