A simplified scoring system in de novo follicular lymphoma treated initially with immunochemotherapy

Author:

Bachy Emmanuel1ORCID,Maurer Matthew J.2,Habermann Thomas M.3,Gelas-Dore Bénédicte4,Maucort-Boulch Delphine56,Estell Jane A.78,Van den Neste Eric9,Bouabdallah Réda10,Gyan Emmanuel11,Feldman Andrew L.12,Bargay Joan13,Delmer Alain14,Slager Susan L.2,Gomes da Silva Maria15,Fitoussi Olivier16,Belada David1718,Maisonneuve Hervé19,Intragumtornchai Tanin20,Ansell Stephen M.3,Lamy Thierry21,Dartigues Peggy22,Link Brian K.23,Seymour John F.24,Cerhan James R.2,Salles Gilles1

Affiliation:

1. Department of Hematology, Hospices Civils de Lyon and Université Claude Bernard, Université de Lyon, INSERM102, Centre National de la Recherche Scientifique (CNRS)5286, Pierre-Bénite, France;

2. Department of Health Sciences Research, Mayo Clinic, Rochester, MN;

3. Division of Hematology, Mayo Clinic, Rochester, MN;

4. Deparment of Biostatistics, Lysarc, Lyon, France;

5. Hospices Civils de Lyon, Service de Biostatistique et Bioinformatique & Université Lyon 1, Lyon, France;

6. CNRS, Unité Mixte de Recherche 5558, Laboratoire de Biométrie et Biologie Evolutive, Equipe Biostatistique-Santé, Villeurbanne, France;

7. Department of Haematology, Concord Repatriation General Hospital, Concord, Sydney, NSW, Australia;

8. Sydney Medical School, University of Sydney, Sydney, NSW, Australia;

9. Hematology Department, Cliniques Universitaires UCL Saint-Luc, Brussels, Belgium;

10. Institut Paoli Calmettes, Marseille, France;

11. Department of Hematology, Centre Hospitalier Universitaire (CHU) de Tours, Tours, France;

12. Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN;

13. Hospital Son Llàtzer, Palma de Mallorca, Spain;

14. CHU de Reims and Université Reims Champagne Ardenne, Reims, France;

15. Portuguese Institute of Oncology, Lisbon, Portugal;

16. Polyclinique Bordeaux Nord Aquitaine, Bordeaux, France;

17. 4th Department of Internal Medicine–Hematology, University Hospital, Hradec Kralove, Czech Republic;

18. Faculty of Medicine, Charles University in Prague, Hradec Kralove, Czech Republic;

19. Centre Hospitalier de la Roche sur Yon, Roche sur Yon, France;

20. Chulalongkorn University, Bangkok, Thailand;

21. Centre Hospitalier Pontchaillou, Rennes, France;

22. Institut Gustave Roussy, Villejuif, France;

23. Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA; and

24. Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, VIC, Australia

Abstract

Key PointsIn FL, no prognostic index has been built based solely on a large cohort of patients treated with initial immunochemotherapy. The PRIMA-PI is a simplified index based on β2m and bone marrow involvement for patients treated with immunochemotherapy.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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