Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide-Reference-Cited by-同舟云学术

Clinical implications of cancer gene mutations in patients with chronic lymphocytic leukemia treated with lenalidomide

Published:2018-04-19 Issue:16 Volume:131 Page:1820-1832
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Takahashi Koichi¹²³^ORCID,Hu Boyu⁴,Wang Feng²,Yan Yuanqing⁵,Kim Ekaterina¹,Vitale Candida¹,Patel Keyur P.⁶,Strati Paolo⁴,Gumbs Curtis²,Little Latasha²,Tippen Samantha²,Song Xingzhi⁷,Zhang Jianhua²,Jain Nitin¹,Thompson Philip¹,Garcia-Manero Guillermo¹,Kantarjian Hagop¹,Estrov Zeev¹,Do Kim-Anh⁵,Keating Michael¹,Burger Jan A.¹,Wierda William G.¹,Futreal P. Andrew²,Ferrajoli Alessandra¹

Affiliation:

1. Department of Leukemia and

2. Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX;

3. Department of Hematology and Oncology, Kyoto University School of Medicine, Kyoto, Japan; and

4. Division of Cancer Medicine,

5. Department of Biostatistics,

6. Department of Hematopathology, and

7. Applied Cancer Science Institute, The University of Texas MD Anderson Cancer Center, Houston, TX

Abstract

Key Points Cancer gene mutations affect treatment response and survival in patients with CLL treated with lenalidomide. The assessment of cancer gene mutations may be useful in the risk stratification of CLL patients.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/131/16/1820/1468016/blood817296.pdf

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