Identification of glycans on plasma-derived ADAMTS13-Reference-Cited by-同舟云学术

Identification of glycans on plasma-derived ADAMTS13

Published:2016-11-24 Issue:21 Volume:128 Page:e51-e58
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Verbij Fabian C.¹,Stokhuijzen Eva¹²,Kaijen Paul H. P.¹,van Alphen Floris¹,Meijer Alexander B.¹³,Voorberg Jan¹

Affiliation:

1. Department of Plasma Proteins, Sanquin-Academic Medical Center Landsteiner Laboratory, Amsterdam, The Netherlands;

2. Emma Children’s Hospital, Academic Medical Center, Amsterdam, The Netherlands; and

3. Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands

Abstract

Key Points ADAMTS13 contains complex type N-linked glycans, which contain terminal mannose, sialic acids, and fucose residues. TSP1 repeats are modified by O-fucosylation and C-mannosylation; O-fucosylation was also observed in the disintegrin domain.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/128/21/e51/1397095/blood720912.pdf

Reference38 articles.

1. Structure-function and regulation of ADAMTS-13 protease;Zheng;J Thromb Haemost,2013

2. FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay;Kokame;Br J Haematol,2005

3. ADAMTS13 autoantibodies in patients with thrombotic microangiopathies and other immunomediated diseases;Rieger;Blood,2005

4. VH1-69 germline encoded antibodies directed towards ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura;Pos;J Thromb Haemost,2009

5. An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF;Pos;Blood,2010

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