Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism-Reference-Cited by-同舟云学术

Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism

Published:2017-03-30 Issue:13 Volume:129 Page:1831-1839
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Riedl Julia¹²,Preusser Matthias²³,Nazari Pegah Mir Seyed¹²,Posch Florian¹²⁴,Panzer Simon⁵,Marosi Christine²³,Birner Peter⁶,Thaler Johannes¹²,Brostjan Christine⁷,Lötsch Daniela²⁸,Berger Walter²⁸,Hainfellner Johannes A.⁹,Pabinger Ingrid¹²,Ay Cihan¹²¹⁰

Affiliation:

1. Clinical Division of Hematology and Hemostaseology, Department of Medicine I, Medical University of Vienna, Vienna, Austria;

2. Comprehensive Cancer Center Vienna, Vienna, Austria;

3. Clinical Division of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria;

4. Clinical Division of Oncology, Department of Medicine, Medical University of Graz, Graz, Austria;

5. Department of Blood Group Serology and Transfusion Medicine,

6. Clinical Institute of Pathology,

7. Department of Surgery,

8. Institute of Cancer Research, Department of Medicine I, and

9. Institute of Neurology, Medical University of Vienna, Vienna, Austria; and

10. Thrombosis and Hemostasis Program, McAllister Heart Institute, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC

Abstract

Key Points Brain tumor patients have a very high risk of VTE. Podoplanin expression by primary brain tumors induces platelet aggregation and is associated with hypercoagulability and a high risk of VTE.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/13/1831/1399229/blood720714.pdf

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