Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions-Reference-Cited by-同舟云学术

Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions

Published:2017-04-27 Issue:17 Volume:129 Page:2443-2454
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Muczynski Vincent¹²,Aymé Gabriel¹,Regnault Véronique³,Vasse Marc¹⁴,Borgel Delphine¹⁵,Legendre Paulette¹,Bazaa Amine¹,Harel Amélie¹,Loubière Cécile¹,Lenting Peter J.¹,Denis Cécile V.¹,Christophe Olivier D.¹

Affiliation:

1. Institut National de la Santé et de la Recherche Médicale, Unité Mixte de Recherche (UMR)_S 1176, University Paris-Sud, Université Paris-Saclay, Le Kremlin-Bicêtre, France;

2. Inovarion SAS, Paris, France;

3. Institut National de la Santé et de la Recherche Médicale, UMR_S 1116, Université de Lorraine, Vandoeuvre-lès-Nancy, France;

4. Biology Department, Hôpital Foch, Suresnes, France; and

5. Assistance Public–Hôpiteaux de Paris, Service d'Hématologie Biologique, Hôpital Necker, Paris, France

Abstract

Key Points We have identified PTX2 as a novel partner for FX in the circulation, and their plasma levels are interdependent. FX and PTX2 cooperate with SR-AI to prevent their uptake by macrophages.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/17/2443/1400315/blood724351.pdf

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