A novel PTPN1 splice variant upregulates JAK/STAT activity in classical Hodgkin lymphoma cells-Reference-Cited by-同舟云学术

A novel PTPN1 splice variant upregulates JAK/STAT activity in classical Hodgkin lymphoma cells

Published:2017-03-16 Issue:11 Volume:129 Page:1480-1490
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Zahn Malena¹,Marienfeld Ralf¹,Melzner Ingo¹,Heinrich Janine¹,Renner Benjamin¹,Wegener Silke¹,Mießner Anna¹,Barth Thomas F. E.¹,Dorsch Karola¹,Brüderlein Silke¹,Möller Peter¹

Affiliation:

1. Institute of Pathology, Ulm University, Ulm, Germany

Abstract

Key Points A novel PTP1B variant, PTP1BΔ6, is expressed in cHL cell lines and tumor samples. PTP1BΔ6 augments JAK/STAT activity, cell proliferation, and survival in cHL cell lines.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/11/1480/1398578/blood720516.pdf

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