Cytohesin 1 regulates homing and engraftment of human hematopoietic stem and progenitor cells-Reference-Cited by-同舟云学术

Cytohesin 1 regulates homing and engraftment of human hematopoietic stem and progenitor cells

Published:2017-02-23 Issue:8 Volume:129 Page:950-958
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Rak Justyna¹^ORCID,Foster Katie²,Potrzebowska Katarzyna³,Talkhoncheh Mehrnaz Safaee¹^ORCID,Miharada Natsumi¹,Komorowska Karolina¹^ORCID,Torngren Therese⁴,Kvist Anders⁴^ORCID,Borg Åke⁴^ORCID,Svensson Lena³^ORCID,Bonnet Dominique²,Larsson Jonas¹

Affiliation:

1. Division of Molecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund, Sweden;

2. Haematopoietic Stem Cell Laboratory, The Francis Crick Institute, London, United Kingdom; and

3. Division of Immunology and

4. Division of Oncology and Pathology, Lund University, Lund, Sweden

Abstract

Key Points RNA interference screen targeted to primary human HSPCs identified CYTH1 as a crucial mediator of cell adhesion. CYTH1 is required for homing and proper bone marrow localization of HSPCs following transplantation.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/129/8/950/1465364/blood720649.pdf

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5. Rho GTPases in hematopoietic stem cell functions;Cancelas;Curr Opin Hematol,2009

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