Platelet WDR1 suppresses platelet activity and is associated with cardiovascular disease-Reference-Cited by-同舟云学术

Platelet WDR1 suppresses platelet activity and is associated with cardiovascular disease

Published:2016-10-20 Issue:16 Volume:128 Page:2033-2042
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Montenont Emilie¹,Echagarruga Christina¹,Allen Nicole¹,Araldi Elisa²,Suarez Yajaira²,Berger Jeffrey S.¹³

Affiliation:

1. Divisions of Cardiology and Hematology, Department of Medicine, New York University School of Medicine, New York, NY;

2. Section of Comparative Medicine and Department of Pathology, Yale University School of Medicine, New Haven, CT; and

3. Division of Vascular Surgery, Department of Surgery, New York University School of Medicine, New York, NY

Abstract

Key Points Platelet transcription of WDR1 suppresses platelet activity. Reduced transcription of WDR1 in platelets may be a link between elevated platelet activity and increased risk of cardiovascular disease.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/128/16/2033/1396813/2033.pdf

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4. Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets.;Denis;Cell,2005

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