CD40 stimulation sensitizes CLL cells to lysosomal cell death induction by type II anti-CD20 mAb GA101
Author:
Affiliation:
1. Departments of Hematology,
2. Experimental Immunology,
3. Cell Biology and Histology, and
4. Biochemistry, Academic Medical Centre, Amsterdam, The Netherlands; and
5. Pharma Research and Early Development, Roche Glycart AG, Schlieren, Switzerland
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/118/19/5178/1345608/zh804511005178.pdf
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4. CD40 stimulation of B-cell chronic lymphocytic leukaemia cells enhances the anti-apoptotic profile, but also Bid expression and cells remain susceptible to autologous cytotoxic T-lymphocyte attack.;Kater;Br J Haematol,2004
5. Triggering of CD40 antigen inhibits fludarabine-induced apoptosis in B chronic lymphocytic leukemia cells.;Romano;Blood,1998
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