Genetic interaction between Kit and Scl-Reference-Cited by-同舟云学术

Genetic interaction between Kit and Scl

Published:2013-08-15 Issue:7 Volume:122 Page:1150-1161
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Lacombe Julie¹,Krosl Gorazd¹²,Tremblay Mathieu¹,Gerby Bastien¹,Martin Richard¹,Aplan Peter D.³,Lemieux Sebastien¹,Hoang Trang¹⁴⁵⁶

Affiliation:

1. Institute for Research in Immunology and Cancer, Montréal, QC, Canada;

2. Maisonneuve-Rosemont Hospital Research Center, Montréal, QC, Canada;

3. Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD; and

4. Department of Pharmacology,

5. Program of Molecular Biology, Department of Computer Science and Operations Research, and

6. Department of Biochemistry, Université de Montréal, Montréal, QC, Canada

Abstract

Key Points Scl operates both downstream of Kit to control the survival of Kit+ multipotent and erythroid progenitors and upstream of Kit to determine Kit expression levels. Scl and Kit establish a positive feedback loop in hematopoietic progenitors.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/7/1150/1374040/1150.pdf

Reference56 articles.

1. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates.;Laslo;Cell,2006

2. Regulation of hematopoietic stem cells by the steel factor/KIT signaling pathway.;Kent;Clin Cancer Res,2008

3. The cellular basis of the genetically determined hemopoietic defect in anemic mice of genotype Sl-Sld.;McCulloch;Blood,1965

4. Spleen-colony formation in anemic mice of genotype WW.;McCulloch;Science,1964

5. Expression of c-kit gene products in known cellular targets of W mutations in normal and W mutant mice—evidence for an impaired c-kit kinase in mutant mice.;Nocka;Genes Dev,1989

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mesenchymal-hämatopoetische Stammzellachse: Anwendungen für die Induktion von hämatopoetischem Chimärismus und Therapien für bösartige Erkrankungen;Stammzellen;2023

2. A Positive Regulatory Feedback Loop Between EKLF/ KLF1 and TAL1/SCL Sustaining the Erythropoiesis;2021-04-08

3. New Insights on the Role of the Mesenchymal–Hematopoietic Stem Cell Axis in Autologous and Allogeneic Hematopoiesis;Stem Cells and Development;2021-01-01

4. Mesenchymal–Hematopoietic Stem Cell Axis: Applications for Induction of Hematopoietic Chimerism and Therapies for Malignancies;Stem Cells;2021

5. Hematopoietic stem and progenitor cell signaling in the niche;Leukemia;2020-10-19