Identification of a gain-of-function STAT3 mutation (p.Y640F) in lymphocytic variant hypereosinophilic syndrome

Author:

Walker Sarah1,Wang Chen2,Walradt Trent2,Hong Bok Sil2,Tanner Justin R.3,Levinsohn Jonathan L.2,Goh Gerald4,Subtil Antonio2,Lessin Stuart R.5,Heymann Warren R.67,Vonderheid Eric C.8,King Brett A.2,Lifton Richard P.91011,Choi Jaehyuk231213ORCID

Affiliation:

1. Dana-Farber Cancer Institute, Boston, MA;

2. Department of Dermatology, Yale School of Medicine, New Haven, CT;

3. Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL;

4. University College London Cancer Institute, London, United Kingdom;

5. Division of Dermatology, Fox Chase Cancer Center, University of Pennsylvania, Philadelphia, PA;

6. Division of Dermatology, Cooper Medical School of Rowan University, Camden, NJ;

7. Department of Dermatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;

8. Sidney Kimmel Cancer Center, Johns Hopkins Medical Institutes, Baltimore, MD;

9. Department of Genetics,

10. Howard Hughes Medical Institute, and

11. Yale Center for Mendelian Genomics, Yale School of Medicine, New Haven, CT;

12. Department of Dermatology, Department of Veterans Affairs Connecticut Healthcare, West Haven, CT; and

13. Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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