Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo-Reference-Cited by-同舟云学术

Cooperative integrin/ITAM signaling in platelets enhances thrombus formation in vitro and in vivo

Published:2013-03-07 Issue:10 Volume:121 Page:1858-1867
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Zhi Huiying¹,Rauova Lubica²,Hayes Vincent²,Gao Cunji¹,Boylan Brian¹,Newman Debra K.¹³⁴,McKenzie Steven E.⁵,Cooley Brian C.⁶,Poncz Mortimer²,Newman Peter J.¹⁴⁷⁸

Affiliation:

1. Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI;

2. Division of Hematology, Children’s Hospital of Philadelphia, Philadelphia, PA;

3. Department of Microbiology and

4. Department of Pharmacology, Medical College of Wisconsin, Milwaukee, WI;

5. Cardeza Foundation for Hematological Research, Department of Medicine, Thomas Jefferson University, Philadelphia, PA; and

6. Department of Orthopaedic Surgery,

7. Department of Cellular Biology, and

8. The Cardiovascular Research Center, Medical College of Wisconsin, Milwaukee, WI

Abstract

Key PointsThese data establish FcγRIIa as a physiologically important functional conduit for αIIbβ3-mediated outside-in signaling.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/10/1858/1362814/1858.pdf

Reference49 articles.

1. Genetic and cell biological analysis of integrin outside-in signaling.;Legate;Genes Dev,2009

2. Integrins: dynamic scaffolds for adhesion and signaling in platelets.;Shattil;Blood,2004

3. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling.;Takagi;Cell,2002

4. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics.;Xiao;Nature,2004

5. Detection of integrin alpha IIbbeta 3 clustering in living cells.;Buensuceso;J Biol Chem,2003

Cited by 81 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Platelet FcγRIIA: An emerging regulator and biomarker in cardiovascular disease and cancer;Thrombosis Research;2024-06

2. Platelets in the tumor microenvironment and their biological effects on cancer hallmarks;Frontiers in Oncology;2023-03-03

3. The relative importance of platelet integrins in hemostasis, thrombosis and beyond;Haematologica;2023-01-26

4. Platelets and tyrosine kinase inhibitors: clinical features, mechanisms of action, and effects on physiology;American Journal of Physiology-Cell Physiology;2022-10-01

5. Anchoring IgG-degrading enzymes to the surface of platelets selectively neutralizes antiplatelet antibodies;Blood Advances;2022-08-08