Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent maintenance of the immature state of human dendritic cells-Reference-Cited by-同舟云学术

Aryl hydrocarbon receptor contributes to the MEK/ERK-dependent maintenance of the immature state of human dendritic cells

Published:2013-04-11 Issue:15 Volume:121 Page:e108-e117
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Aguilera-Montilla Noemí¹,Chamorro Sonia¹,Nieto Concha¹,Sánchez-Cabo Fátima²,Dopazo Ana²,Fernández-Salguero Pedro Maria³,Rodríguez-Fernández Jose Luis¹,Pello Oscar M.²,Andrés Vicente²,Cuenda Ana⁴,Alonso Bárbara⁵,Domínguez-Soto Angeles¹,Sánchez-Ramón Silvia⁵,Corbí Angel L.¹

Affiliation:

1. Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain;

2. Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain;

3. Universidad de Extremadura, Badajoz, Spain;

4. Centro Nacional de Biotecnología, CSIC, Madrid, Spain;

5. Hospital General Universitario Gregorio Marañón, Madrid, Spain

Abstract

Key Points Aryl hydrocarbon receptor (AhR) mediates the ERK-dependent maintenance of the immature state of monocyte-derived dendritic cells (MDDCs). MEK-ERK regulates antigen capture, lymph node homing, and the acquisition of maturation-associated genes in MDDCs.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/15/e108/1366257/e108.pdf

Reference50 articles.

1. Decisions about dendritic cells: past, present, and future.;Steinman;Annu Rev Immunol,2012

2. Avoiding horror autotoxicus: the importance of dendritic cells in peripheral T cell tolerance.;Steinman;Proc Natl Acad Sci USA,2002

3. Dendritic cells: emerging pharmacological targets of immunosuppressive drugs.;Hackstein;Nat Rev Immunol,2004

4. Differential role of MAPK signaling in human dendritic cell maturation and Th1/Th2 engagement.;Nakahara;J Dermatol Sci,2006

5. Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells.;Puig-Kröger;Blood,2001

Cited by 38 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. IGF2 contributes to the immunomodulatory effects of exosomes from endometrial regenerative cells on experimental colitis;International Immunopharmacology;2024-10

2. Nutritional Provision of Iron Complexes by the Major Allergen Alt a 1 to Human Immune Cells Decreases Its Presentation;International Journal of Molecular Sciences;2023-07-25

3. A review on immunomodulatory effects of BPA analogues;Archives of Toxicology;2023-05-19

4. Binding to Iron Quercetin Complexes Increases the Antioxidant Capacity of the Major Birch Pollen Allergen Bet v 1 and Reduces Its Allergenicity;Antioxidants;2022-12-26

5. MEK homologue is involved in immune response by regulating antimicrobial peptides expression in Chinese mitten crab Eriocheir sinensis;Developmental & Comparative Immunology;2022-12