The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy-Reference-Cited by-同舟云学术

The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy

Published:2013-02-28 Issue:9 Volume:121 Page:1563-1573
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Mancardi David A.¹²³,Albanesi Marcello¹²³⁴,Jönsson Friederike¹²³,Iannascoli Bruno¹²³,Van Rooijen Nico⁵,Kang Xiaoqiang⁶,England Patrick⁷⁸,Daëron Marc²³,Bruhns Pierre¹²³

Affiliation:

1. Institut Pasteur, Département d'Immunologie, Laboratoire Anticorps en Thérapie et Pathologie, Paris, France;

2. Institut Pasteur, Département d'Immunologie, Unité d'Allergologie Moléculaire et Cellulaire, Paris, France;

3. Inserm, U760, Paris, France;

4. Université Pierre et Marie Curie, Paris, France;

5. Department of Molecular Cell Biology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands;

6. ImClone Systems, New York, NY;

7. Institut Pasteur, Protéopole, Plateforme de Biophysique des Macromolécules et de leurs Interactions, Paris, France; and

8. Centre National de la Recherche Scientifique, Unité Mixte de Recherche 3528, Paris, France

Abstract

Key Points Human FcγRI can trigger antibody-induced inflammatory arthritis, thrombocytopenia, airway inflammation, and systemic anaphylaxis. Human FcγRI can trigger antibody-mediated immunotherapy of mouse metastatic melanoma.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/9/1563/1368733/zh800913001563.pdf

Reference50 articles.

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2. Human FcgammaRIIA induces anaphylactic and allergic reactions.;Jönsson;Blood,2012

3. Development of spontaneous multisystem autoimmune disease and hypersensitivity to antibody-induced inflammation in Fcgamma receptor IIa-transgenic mice.;Tan Sardjono;Arthritis Rheum,2005

4. A novel human CD32 mAb blocks experimental immune haemolytic anaemia in FcgammaRIIA transgenic mice.;van Royen-Kerkhof;Br J Haematol,2005

5. Human neutrophil Fcgamma receptors initiate and play specialized nonredundant roles in antibody-mediated inflammatory diseases.;Tsuboi;Immunity,2008

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