MDS: roadblock to differentiation
Author:
Affiliation:
1. OREGON HEALTH & SCIENCE UNIVERSITY
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/120/10/1968/1356855/zh803612001968.pdf
Reference10 articles.
1. Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations.;Will;Blood,2012
2. Isolation and characterization of hematopoietic progenitor/stem cells in 5q-deleted myelodysplastic syndromes: evidence for involvement at the hematopoietic stem cell level.;Nilsson;Blood,2000
3. Persistent malignant stem cells in del(5q) myelodysplasia in remission.;Tehranchi;N Engl J Med,2010
4. The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes.;Nilsson;Blood,2007
5. Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia.;Goardon;Cancer Cell,2011
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1. Myelodysplastic Syndromes Are Propagated by Rare and Distinct Human Cancer Stem Cells In Vivo;Cancer Cell;2014-06
2. Feedback Signals in Myelodysplastic Syndromes: Increased Self-Renewal of the Malignant Clone Suppresses Normal Hematopoiesis;PLoS Computational Biology;2014-04-24
3. BMI1 reprogrammes histone acetylation and enhances c‐fos pathway via directly binding to Zmym3 in malignant myeloid progression;Journal of Cellular and Molecular Medicine;2014-02-27
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