In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells-Reference-Cited by-同舟云学术

In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells

Published:2013-02-21 Issue:8 Volume:121 Page:1255-1264
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Amabile Giovanni¹²³,Welner Robert S.¹²³,Nombela-Arrieta Cesar²⁴,D'Alise Anna Morena¹²,Di Ruscio Annalisa¹²³,Ebralidze Alexander K.¹²³,Kraytsberg Yevgenya¹³,Ye Min¹²³,Kocher Olivier¹,Neuberg Donna S.⁵,Khrapko Konstantin¹³,Silberstein Leslie E.²⁴,Tenen Daniel G.¹²⁶

Affiliation:

1. Harvard Medical School, Boston, MA;

2. Harvard Stem Cell Institute, Boston, MA;

3. Department of Hematology/Oncology, Beth Israel Deaconess Medical Center, Boston, MA;

4. Department of Laboratory Medicine, Joint Program in Transfusion Medicine, Children's Hospital, Boston, MA;

5. Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA; and

6. Cancer Science Institute, National University of Singapore, Singapore

Abstract

Key Points Human hematopoietic cells develop within human iPSC-derived teratomas in immunodeficient mice. Co-transplantation of OP9 stromal cells along with human iPSCs increases hematopoietic specification within teratomas.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/8/1255/1369086/zh800813001255.pdf

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4. Induction of pluripotent stem cells from adult human fibroblasts by defined factors.;Takahashi;Cell,2007

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