1. Department of Biology and Biotechnology, Division of Biochemistry, and
2. Department of Molecular Medicine, University of Pavia, Pavia, Italy;
3. Department of Internal Medicine, University of Perugia, Perugia, Italy;
4. Department of Infectious Diseases, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy;
5. Blizard Institute, Queen Mary University of London, London, United Kingdom; and
6. Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan