Cooperating gene mutations in childhood acute myeloid leukemia with special reference on mutations of ASXL1, TET2, IDH1, IDH2, and DNMT3A-Reference-Cited by-同舟云学术

Cooperating gene mutations in childhood acute myeloid leukemia with special reference on mutations of ASXL1, TET2, IDH1, IDH2, and DNMT3A

Published:2013-04-11 Issue:15 Volume:121 Page:2988-2995
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Liang Der-Cherng¹,Liu Hsi-Che¹,Yang Chao-Ping²,Jaing Tang-Her²,Hung Iou-Jih²,Yeh Ting-Chi¹,Chen Shih-Hsiang²,Hou Jen-Yin¹,Huang Ying-Jung³,Shih Yu-Shu⁴,Huang Yu-Hui⁴,Lin Tung-Huei⁴,Shih Lee-Yung³⁴

Affiliation:

1. Division of Pediatric Hematology-Oncology, Mackay Memorial Hospital, Taipei, Taiwan;

2. Department of Hematology-Oncology, Chang Gung Children’s Hospital, Taoyuan, Taiwan;

3. Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan; and

4. Chang Gung University, Taoyuan, Taiwan

Abstract

Key Points A comprehensive study of 19 gene mutations and their cooperation, including the first report of ASXL1 and TET2 mutations in pediatric AML. The development of pediatric AML requires fewer gene mutations than adult AML.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/15/2988/1364829/2988.pdf

Reference50 articles.

1. Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor.;Cho;J Biol Chem,2006

2. Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia.;Fisher;Blood,2010

3. ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.;Abdel-Wahab;Cancer Cell,2012

4. Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations.;Chou;Blood,2010

5. Acquired mutations in ASXL1 in acute myeloid leukemia: prevalence and prognostic value.;Pratcorona;Haematologica,2012

Cited by 74 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Prognosis and treatment in acute myeloid leukemia: a comprehensive review;Egyptian Journal of Medical Human Genetics;2024-08-06

2. Aberrant stem cell and developmental programs in pediatric leukemia;Frontiers in Cell and Developmental Biology;2024-03-27

3. Chromosomal and Genomic Alterations in Pediatric AML;Pediatric Oncology;2024

4. Role of Gene Mutations in Acute Myeloid Leukemia: A Review Article;Global Medical Genetics;2023-06

5. RUNX1 mutation has no prognostic significance in paediatric AML: a retrospective study of the AML-BFM study group;Leukemia;2023-05-15