In Adults with Ph-Negative Acute Lymphoblastic Leukemia (ALL), Age-Adapted Chemotherapy Intensity and MRD-Driven Transplant Indication Significantly Reduces Treatment-Related Mortality (TRM) and Improves Overall Survival - Results from the Graall-2014 Trial-Reference-Cited by-同舟云学术

In Adults with Ph-Negative Acute Lymphoblastic Leukemia (ALL), Age-Adapted Chemotherapy Intensity and MRD-Driven Transplant Indication Significantly Reduces Treatment-Related Mortality (TRM) and Improves Overall Survival - Results from the Graall-2014 Trial

Published:2022-11-15 Issue:Supplement 1 Volume:140 Page:112-114
ISSN:0006-4971
Container-title:Blood
language:en
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Author:

Boissel Nicolas¹²,Huguet Francoise³,Leguay Thibaut⁴,Mathilde Hunault-Berger⁵,Graux Carlos⁶,Chalandon Yves⁷,Delabesse Eric⁸,Hicheri Yosr⁹,Chevallier Patrice¹⁰,Balsat Marie¹¹,Pastoret Cedric¹²,Escoffre-Barbe Martine¹³,Pasquier Florence¹⁴,Marolleau Jean-Pierre¹⁵,Thiebaut-Bertrand Anne¹⁶,Huynh Anne¹⁷,Dhedin Nathalie¹⁸,Lemasle Emilie¹⁹,Bonmati Caroline²⁰,Maury Sébastien²¹,Guillerm Gaëlle²²,Berceanu Anna²³,Schanz Urs²⁴,Cluzeau Thomas²⁵,Turlure Pascal²⁶,Rousselot Philippe²⁷,De Prijck Bernard J.M.²⁸,Grardel Nathalie²⁹,Bene Marie C³⁰,Lafage Marine³¹,Ifrah Norbert³²,Lheritier Veronique³³,Asnafi Vahid³⁴³⁵,Clappier Emmanuelle³⁶,Dombret Herve³⁷³⁸

Affiliation:

1. 1St-Louis Hospital, APHP, Adolescent and Young Adult Hematology Department, Paris, France

2. 2URP-3518, Saint-Louis Research Insitute, Université Paris Cité, Paris, France

3. 3Department of Hematology, Institut Universitaire du Cancer-Oncopole CHU de Toulouse, Toulouse, France

4. 4Hematology Clinic, Bordeaux University Hospital, Pessac, France

5. 5department of hematology, CHU Angers, Angers, France

6. 6Université Catholique de Louvain, CHU UCL Namur (Godinne), Yvoir, Belgium

7. 7Geneva University Hospitals, Geneva, Switzerland

8. 8N/A, N/A, FRA

9. 9Departement d'Hematologie, Institut Paoli-Calmettes, MARSEILLE, France

10. 10Hematology Department, Nantes University Hospital, Nantes, France

11. 11Service Hematologie, Centre Hospitalier Lyon Sud, Lyon, France

12. 12INSERM U1236 /Hematology Laboratory, University Hospital of Rennes, RENNES, FRA

13. 13Hôpital de Pontchaillou, Centre Hospitalier Universitaire de Rennes, Rennes, France

14. 14Gustave Roussy, Département clinique d'hématologie, INSERM UMR1170, Villejuif, FRA

15. 15Hematology Department, Amiens University Hospital, Amiens, France

16. 16Department of Hematology, CHU-Grenoble Onco-Hematologie, Grenoble, France

17. 17Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France

18. 18St-Louis Hospital, APHP, Adolescents and Young Adults Hematology Department, Paris, France

19. 19Hematology Department, Henri-Becquerel Cancer Center, Rouen, France

20. 20Service D'Hématologie, Centre Hospitalier Universitaire De Nancy, Nancy, FRA

21. 21Service d'Hématologie clinique, Hôpitaux universitaires Henri-Mondor (AP-HP), Créteil, FRA

22. 22Department of Hematology, Brest University Hospital, Brest, France

23. 23Clinical Hematology, Besançon University Hospital, Besançon, France

24. 24Department of Medical Oncology and Hematology, University Hospital Zurich, Zurich, Switzerland

25. 25Department of Hematology, Université Côte d'Azur, Centre Hospitalier Universitaire, Nice, France

26. 26Department of Clinical Hematology, Limoges University Hospital, Limoges, France

27. 27Hematology Department, Centre Hospitalier de Versailles, LE CHESNAY CEDEX, France

28. 28CHU Sart Tilman, Liege, BEL

29. 29Laboratory of Hematology, Centre Hospitalier Universitaire Lille, Lille, France

30. 30Hematology Biology, Nantes University Hospital, Nantes, France

31. 31Department of Genetics, La Timone Hospital, Aix Marseille University, MARSEILLE, France

32. 32Clinical Hematology, Angers University Hospital, Angers, France

33. 33Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL), Centre Hospitalier Lyon Sud, Lyon, France

34. 34INSERM U1151, Université Paris Descartes Sorbonne Cité, Paris, France

35. 35Laboratory of Onco-Hematology, Necker University Hospital, Paris, France

36. 36Hematology Laboratory, AP-HP, Hôpital Saint-Louis, Paris, France

37. 37URP-3518, Institut de Recherche Saint-Louis, Université Paris Cité, Paris, France

38. 38Hopital Saint-Louis, Assistance Publique - Hopitaux De Paris (AP-HP), Paris, FRA

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

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