Role of anthracycline and comprehensive geriatric assessment for elderly patients with diffuse large B-cell lymphoma-Reference-Cited by-同舟云学术

Role of anthracycline and comprehensive geriatric assessment for elderly patients with diffuse large B-cell lymphoma

Published:2017-11-16 Issue:20 Volume:130 Page:2180-2185
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Lin Richard J.¹^ORCID,Behera Madhusmita²,Diefenbach Catherine S.³,Flowers Christopher R.²

Affiliation:

1. Memorial Sloan Kettering Cancer Center, New York, NY;

2. Winship Cancer Institute, Emory University, Atlanta, GA; and

3. Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY

Abstract

Abstract Survival outcome for elderly patients with newly diagnosed diffuse large B-cell lymphoma remains suboptimal in the rituximab era. In this systematic review, we summarize available evidence relevant to the inclusion of anthracycline in upfront chemoimmunotherapy for these elderly patients and highlight the need of prospective clinical trials. With limited prospective data, we find that pretreatment comprehensive geriatric assessment accurately predicts survival and treatment-related toxicities, suggesting its potential role in guiding overall treatment decision-making.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/130/20/2180/1403319/blood736975.pdf

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