Chemotherapy-only treatment effects on long-term neurocognitive functioning in childhood ALL survivors: a review and meta-analysis-Reference-Cited by-同舟云学术

Chemotherapy-only treatment effects on long-term neurocognitive functioning in childhood ALL survivors: a review and meta-analysis

Published:2015-07-16 Issue:3 Volume:126 Page:346-353
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Iyer Neel S.¹^ORCID,Balsamo Lyn M.²,Bracken Michael B.³,Kadan-Lottick Nina S.²^ORCID

Affiliation:

1. Lake Erie College of Osteopathic Medicine, Erie, PA;

2. Pediatric Hematology/Oncology, Yale School of Medicine and Yale Cancer Center, New Haven, CT; and

3. Department of Epidemiology and Public Health, Yale School of Medicine, New Haven, CT

Abstract

Key Points Children treated for ALL without cranial radiation display significant IQ deficits of 6 to 8 points compared with healthy controls. Moderate deficits occur in other neurocognitive domains including working memory, information processing speed, and fine motor functioning.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/126/3/346/1390660/346.pdf

Reference63 articles.

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