Modified Ham test for atypical hemolytic uremic syndrome-Reference-Cited by-同舟云学术

Modified Ham test for atypical hemolytic uremic syndrome

Published:2015-06-04 Issue:23 Volume:125 Page:3637-3646
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Gavriilaki Eleni¹^ORCID,Yuan Xuan¹,Ye Zhaohui¹,Ambinder Alexander J.¹,Shanbhag Satish P.¹,Streiff Michael B.¹,Kickler Thomas S.²,Moliterno Alison R.¹,Sperati C. John³,Brodsky Robert A.¹

Affiliation:

1. Division of Hematology, Department of Medicine,

2. Department of Pathology, and

3. Division of Nephrology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD

Abstract

Key Points GPI-anchor–deficient cell lines are more vulnerable to complement C5b-9 deposition and cell killing from aHUS serum. PIGA-null reagent cell lines can be used to rapidly and reliably distinguish aHUS from other thrombotic microangiopathies.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/125/23/3637/1387571/3637.pdf

Reference47 articles.

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2. Decreased cold-insoluble globulin in congenital thrombocytopenia (Upshaw-Schulman syndrome).;Rennard;N Engl J Med,1979

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