Prostaglandin E synthase is upregulated by Gas6 during cancer-induced venous thrombosis-Reference-Cited by-同舟云学术

Prostaglandin E synthase is upregulated by Gas6 during cancer-induced venous thrombosis

Published:2016-02-11 Issue:6 Volume:127 Page:769-777
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Aghourian Meghedi N.¹,Lemarié Catherine A.¹²,Bertin Francois-René¹,Blostein Mark D.¹²

Affiliation:

1. Lady Davis Institute and

2. Department of Medicine, Jewish General Hospital, McGill University, Montreal, QC, Canada

Abstract

Key Points Gas6 promotes cancer-induced thrombosis by regulating the expression of Ptges from the endothelium. Gas6-dependent PGE2 secretion from the endothelium leads to platelet activation and venous thrombosis.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/127/6/769/1394563/769.pdf

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