Imatinib disrupts lymphoma angiogenesis by targeting vascular pericytes-Reference-Cited by-同舟云学术

Imatinib disrupts lymphoma angiogenesis by targeting vascular pericytes

Published:2013-06-27 Issue:26 Volume:121 Page:5192-5202
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Ruan Jia¹,Luo Min²,Wang Chunjie¹,Fan Lei¹,Yang Shao Ning¹,Cardenas Mariano¹,Geng Huimin¹,Leonard John P.¹,Melnick Ari¹,Cerchietti Leandro¹,Hajjar Katherine A.²

Affiliation:

1. Division of Hematology/Oncology, Department of Medicine, and

2. Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY

Abstract

Key Points Blockade of PDGFRβ impairs lymphoma growth by depleting vascular mural cells. Pericytes may represent a novel, antiangiogenic target for lymphoma therapy.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/121/26/5192/1367125/5192.pdf

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