Human regulatory T cells against minor histocompatibility antigens: ex vivo expansion for prevention of graft-versus-host disease-Reference-Cited by-同舟云学术

Human regulatory T cells against minor histocompatibility antigens: ex vivo expansion for prevention of graft-versus-host disease

Published:2013-09-26 Issue:13 Volume:122 Page:2251-2261
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

Veerapathran Anandharaman¹²,Pidala Joseph¹²,Beato Francisca¹²,Betts Brian¹,Kim Jongphil³,Turner Joel G.¹,Hellerstein Marc K.⁴⁵,Yu Xue-Zhong¹²,Janssen William¹²,Anasetti Claudio¹²

Affiliation:

1. Department of Blood and Marrow Transplantation,

2. Department of Immunology, and

3. Department of Biostatistics, Moffitt Cancer Center, Tampa, FL;

4. Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, CA; and

5. Department of Medicine, University of California at San Francisco, San Francisco, CA

Abstract

Key Points This is the first report about the detection of human Tregs specific for minor histocompatibility antigens. We detected, quantified, and cloned mHA-specific Tregs and expanded these potent Tregs in sufficient numbers for use in human transplantation.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/122/13/2251/1367894/2251.pdf

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