Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations-Reference-Cited by-同舟云学术

Genetic profile of T-cell acute lymphoblastic leukemias with MYC translocations

Published:2014-12-04 Issue:24 Volume:124 Page:3577-3582
ISSN:0006-4971
Container-title:Blood
language:en
Short-container-title:

Author:

La Starza Roberta¹,Borga Chiara²,Barba Gianluca¹,Pierini Valentina¹,Schwab Claire³,Matteucci Caterina¹,Lema Fernandez Anair G.¹,Leszl Anna²,Cazzaniga Gianni⁴,Chiaretti Sabina⁵,Basso Giuseppe²,Harrison Christine J.³,te Kronnie Geertruy²,Mecucci Cristina¹

Affiliation:

1. Hematology Unit, University of Perugia, Polo Unico S.M. Misericordia, Perugia, Italy;

2. Oncohematology, Department of Women’s and Children’s Health, University of Padova, Padova, Italy;

3. Leukaemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle-upon-Tyne, United Kingdom;

4. Centro Ricerca Tettamanti, Pediatric Clinic University of Milano-Bicocca, Monza, Italy; and

5. Division of Hematology, “Sapienza” University of Rome, Rome, Italy

Abstract

Key Points MYC translocations represent a genetic subgroup of NOTCH1-independent T-ALL clustered within the TAL/LMO category. MYC translocations are secondary abnormalities, which appear to be associated with induction failure and relapse.

Publisher

American Society of Hematology

Subject

Cell Biology,Hematology,Immunology,Biochemistry

Link

http://ashpublications.org/blood/article-pdf/124/24/3577/1381539/3577.pdf

Reference25 articles.

1. Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia.;Kleppe;Nat Genet,2010

2. PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability.;Silva;J Clin Investig,2008

3. NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols.;Zuurbier;Leukemia,2010

4. HES1 opposes a PTEN-dependent check on survival, differentiation, and proliferation of TCRβ-selected mouse thymocytes.;Wong;Blood,2012

5. Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation.;Guo;Nature,2008

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