1. Cardiovascular Sciences, National Heart and Lung Institute, Faculty of Medicine, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, London, United Kingdom;
2. Medical Research Council Laboratory of Molecular Cell Biology, Cell Biology Unit and Department of Cell and Developmental Biology, University College London, London, United Kingdom;
3. Airway Disease Department, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, United Kingdom;
4. Department of Haematology, Hammersmith Campus, Imperial College Academic Health Sciences Centre, Imperial College London, London, United Kingdom; and
5. International Centre for Circulatory Health, National Heart and Lung Institute, Faculty of Medicine, Imperial College London and Imperial College Healthcare National Health Service Trust, London, United Kingdom